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Antimicrobial Prophylaxis in Surgery

Antimicrobial prophylaxis can decrease the incidence of infection, particularly wound infection after certain operation, but this benefit must be weighed against cost, risks of toxic or allergic reactions, and emergence of resistant bacteria. The administration of antibiotic agents to prevent infection cannot be substituted for Surgical wounds may be designated as clean, contaminated, or dirty, […]

Use of Blood Transfusion in Surgery

The golden rule of blood transfusion should be that no transfusion is given unless the benefit of the transfusion outweighs the risks. Before all blood transfusion,therefore,there must be a balance among the risks associated with the transfusion, the indications for transfusion, and the availability and benefit of using alternatives to conventional transfusion. The following is […]


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